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Domestication had a destructive effect on Dog’s DNA

A new research has come up with a woeful study which states that domesticating dogs from gray wolves more than 15,000 years ago involved artificial selection and inbreeding, and eventually this process may have inadvertently caused harmful genetic changes in our canine pets.

The researchers examined the whole genome sequences of 19 wolves, 25 wild dogs from 10 different countries, and 46 domesticated dogs from 34 different breeds.

Following the study, the results depicted that domestication is responsible in the increase of the number of harmful genetic changes in dogs which might be is the consequence of temporary reductions in population size known as bottlenecks.

“Population bottlenecks tied to domestication, rather than recent inbreeding, likely led to an increased frequency of deleterious genetic variations in dogs,” said senior author of the research Kirk Lohmueller, assistant professor of ecology and evolutionary biology at University of California, Los Angeles.

“Our research suggests that such variants may have piggybacked onto positively selected regions, which were also enriched in disease-related genes,” Lohmueller said.

“Thus, the use of small populations artificially bred for desired traits, such as smaller body size or coat colour, may have led to an accumulation of harmful genetic variations in dogs,” Lohmueller noted.

Moreover, such random variations due to domestication , Lohmueller said, could potentially lead to a number of different developmental disorders and other health risks.

The research was published in the journal Proceedings of the National Academy of Sciences (PNAS).

So keep a wider check upon the domestication manner.

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